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Category Archive for 'Channels'

Memories are made of this

Some of you have mastered the art of cramming for exams. But what really happens when we store a thought for a very short period of time? What are memories made of? We’ve come a long way in our understanding since Dean Martin’s 1955 hit song. After looking at single neurons in the prefrontal cortex [...]

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Peppers Pamper a Peck of Pain

By at least one measure surgical pain management techniques haven’t changed significantly since the first use of ether at Massachusetts General Hospital (MGH) in Charlestown in 1846. Anesthetics—both general and local—work by blocking or interfering with signals from all neurons, not just the pain-sensing ones. While these techniques do block pain, they come with a [...]

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Typically, the arsenal of pscho-active anti-depressants can take weeks if not months to take effect. But recent research has shown that ketamines can relieve symptoms of depression in a matter of hours. Ketamines appear to be NMDA antagonists; this can mediate LTD by stopping the sequestering of AMPA receptors. There may be [...]

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“In the lecture material given on 7/13 about drugs binding to the Cl channels. I am mostly confused about what the drugs do. I have written down that Benzodiazepine depolarizes the membrane to the voltage of equilibrium for Cl (according to the Nernst Equation). I also have written down that certain drugs inhibit the neuron [...]

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